The research in Dr. Hung’s group aims on the development of novel methodologies for the synthesis of biologically potent oligosaccharides, glycolipids, and glycoproteins via a combination of regioselective one-pot protection and stereoselective one-pot glycosylation. The major interests include five topics:
Discovery of new technologies for carbohydrate synthesis
Preparation of cell-surfaced carbohydrates (heparin/heparan sulfate, GPI anchors) and mycobacterial cell envelope components
Development of heparin-related microarrays, dendrimers, and nanoparticles
Study of heparin-protein interaction
Investigation of carbohydrate-based anti-tuberculosis vaccines